FRCA Notes


Neural pathways of the eyes


  • Free nerve endings of Aδ and C-fibres detect painful or noxious stimuli
  • These are nerve endings of the frontal, lachrymal and nasociliary nerves

  • The nasociliary nerve supplies sensation to the cornea, perilimbal conjunctiva and supero-nasal peripheral conjunctiva
    • It also supplies the long and short ciliary nerves
  • The lacrimal and frontal nerves supply sensation to the remaining peripheral conjunctiva

  • These three musketeers pass through the superior orbital fissure
  • They unite to form the ophthalmic division (V1) of the trigeminal nerve

  • The cell bodies of these neurons lie within the semi-lunar (trigeminal) ganglion
  • They project to the pons before ultimately terminating in the sensory trigeminal nuclei

  • The nerves supplying motor functions enter via the superior orbital fissure

  • Oculomotor nerve (CN III)
    • Supplies the medial, inferior and superior rectus muscles
    • Supplies the inferior oblique muscle

  • Trochlear nerve (CN IV)
    • Supplies the superior oblique muscle (SO4)

  • Abducens nerve (CN VI)
    • Supplies the lateral rectus muscle (LR6)

  • Inhibition of the motor components of these nerves provides akinesis of the globe
  • Intra-conal injection may spare the trochlear nerve (which follows an extra-conal path) leading to inadequate akinesis of superior oblique

  • The optic nerve leaves the globe postero-medially
  • It passes through the orbit and exits via the optic foramen
  • It is vulnerable to injury e.g. during retrobulbar block with an overly-long needle or if the patient looks supero-nasally