FRCA Notes


Arthroplasty


  • Patients undergoing primary elective arthroplasty are most often doing so for osteoarthritis
  • They may, although not always, be younger and less comorbid

Secondary (revision)

  • Patients undergoing secondary arthroplasty tend to be more complex, on account of:
    • Being older
    • Having a greater number of comorbidities
    • Having suffered a complication requiring a revision e.g. fracture, recurrent dislocation, infection or prosthesis failure

  • Revision arthroplasties therefore tend to be:
    • Longer, either as stand-alone operations or as two-stage revisions
    • Associated with greater blood loss

Anaesthesia

  • Neuraxial techniques are generally preferred
  • Options include spinal anaesthesia, CSE or epidural techniques
    • Spinal anaesthesia is recommended by multiple guidelines

  • ± procedural sedation
    • Usually propofol TCI
    • Patient-controlled procedural sedation is associated with fewer sedation-associated adverse events than anaesthetist-led TCI (BJA, 2021)

  • General anaesthesia, combined with regional analgesic techniques, for those in whom neuraxial techniques are contra-indicated or have failed

Analgesia

  • ± consider 100mcg morphine intrathecally if spinal anaesthetic used
  • Single-shot fascia iliaca block or local wound LA infiltration

  • Simple analgesia (paracetamol + NSAID if not contraindicated) either pre- or intra-operatively
  • Single dose of intra-operative dexamethasone for analgesic properties
  • Consider intra-operative adjuncts such as:
    • Ketamine 0.1-0.3mg/kg IV
    • Magnesium 50mg/kg IV over 30mins

  • Post-operatively:
    • Regular paracetamol
    • Consider NSAID with PPI cover
    • Consider nefopam in those not able to have NSAIDs
    • Reserve opioids for rescue analgesia (consider oxycodone rather than morphine)

  • Compared with THR, is associated with greater degrees of post-operative pain on account of:
    • Extensive osteotomy
    • Splitting of the quadriceps muscle
  • Conversely, there is less blood loss owing to relevant anatomy and use of tourniquets

Anaesthesia

  • Neuraxial techniques are generally preferred
  • Options include spinal anaesthesia, CSE or epidural techniques
    • Spinal anaesthesia is recommended by multiple guidelines
  • ± propofol TCI sedation

  • General anaesthesia, combined with regional analgesic techniques, for those in whom neuraxial techniques are contra-indicated or have failed

Analgesia

  • Simple analgesia (paracetamol + NSAID if not contraindicated) either pre- or intra-operatively
  • Consider single dose of pre-operative, long-acting opioid

  • Single dose of intra-operative dexamethasone for analgesic properties (higher doses not superior to lower doses)
  • Consider intra-operative adjuncts such as:
    • Intra-articular NSAID
    • Ketamine 0.1-0.3mg/kg IV (although conflicting evidence base)
    • Magnesium 50mg/kg IV over 30mins

  • Peri-operative regional anaesthetic options
    • Adductor canal block
    • IPACK block
    • Local anaesthetic wound infiltration

  • Post-operatively:
    • Regular paracetamol
    • Consider NSAID with PPI cover
    • Consider nefopam in those not able to have NSAIDs
    • Reserve opioids for rescue analgesia (consider oxycodone rather than morphine)
      • Transdermal fentanyl may be as efficacious as fentanyl PCA, with the benefit for improved mobility but a slower onset time
    • Non-pharmacological methods such as cryocuff, which may provide analgesia, physical support and increase ROM

Perioperative care of the patient undergoing elective arthroplasty


  • A full history and examination as standard
  • Adequaate assessment of functional reserve may be difficult owing to:
    • Limitations to function being from pain rather than poor cardiorespiratory reserve
    • Routine pre-operative investigations typically examining the patient at rest and therefore information from these may be limited

Optimisation

  • Address common comorbidities such as anaemia, hypertension and diabetes as standard
  • Use of local ERAS programmes is associated with earlier discharge, increased patient satisfaction, reduced morbidity and potentially reduced mortality
  • 'Joint school' is a form of patient education which can reduce anxiety, though has not been proved to reduce length of stay, post-operative pain or increase post-operative function

Secondary (revision)

  • Patients are older and more comorbid, so require appropriate optimisation
  • Blood loss may be significant; cross-match blood rather than G&S
  • Revision surgery takes longer and single-shot neuraxial anaesthetic techniques may not provide sufficient duration of action
  • Tend to have increased post-operative pain
  • Therefore require appropriate planning for intra-operative techniques and suitable post-operative location e.g. HDU

Choice of technique

  • As ever, anaesthetic techniques will need to be tailored to the individual patient and surgery
  • There is no difference in long-term morbidity or mortality between RA and GA for elective lower limb joint surgery
  • However, regional/neuraxial techniques are associated with reductions in
    • Opioid consumption
    • PONV
    • Post-operative pain
    • Time to mobilisation
    • Length of stay (for TKR)

  • See sections above for THR- and TKR-specific anaesthetic techniques

Monitoring

  • AAGBI as standard
  • May require intra-arterial monitoring if significant cardiorespiratory disease, or secondary arthroplasty
  • Multiple wide-bore cannulae in secondary arthroplasty, given bleeding risk
  • ± CVC
  • Temperature monitoring, as patients at higher risk of hypothermia especially if longer operative times

Positioning

  • Meticulous patient positioning is essential, as the patient population are typically at higher risk
  • Especially so for revision surgery, where operative times are longer
  • Positioning may limit airway access, which might influence choice of airway device

Care bundle

  • Antibiotic prophylaxis as per local guidelines
    • Revision surgery may have specific requirements, tailored to microbiology advice
  • Temperature monitoring and management
  • Intra-operative VTE prophylaxis with mechanical devices

  • Avoid urinary catheterisation
  • Avoid indwelling drains

Haemorrhage

  • Pre-operative cross-match
  • Consider use of cell salvage, especially in revision arthroplasty
  • Give TXA 15mg/kg (pre-operative PO TXA may be as effective as intra-operative IV TXA)
  • Use limb tourniquet in TKR
  • Good communication with the surgical team re: ongoing blood loss

  • HDU care may be indicated, especially for revision arthroplasty owing to:
    • Longer operative time
    • More heavily comorbid patients
    • Greater degree of blood loss
    • Use of techniques not amenable to ward beds e.g. epidural analgesia

  • Analgesia is as per sections above relating to THR and TKR