- Referral for NHS-funded bariatric surgery follows assessment by a specialist weight management surgery
- It is an option if the patient fulfils all the following criteria:
- BMI
- >40kg/m2
- 35 - 40kg/m2 + other significant diseases e.g. HTN, T2DM
- 30 - 35kg/m2 or Asian family origin + recent onset T2DM
- All appropriate non-surgical measures have failed to achieve or maintain clinically beneficial weight loss
- Patient will receive intensive management in a Tier 3 service
- Generally fit for anaesthesia and surgery
- Commits to need for long-term follow-up
Bariatric Surgery
Bariatric Surgery
This topic features in the curriculum as 'Recalls/describes the anaesthetic implications of bariatric surgery'.
Resources
- Obesity is initially treated with lifestyle modification, including education, dietary change and exercise
- If that fails then medical management, as part of specialist-led weight management programmes, can be used as an adjunct in those with BMI >30kg/m2
- E.g. orlistat (lipase inhibitor) or liraglutide (GLP-1 receptor agonist)
- If that too fails, surgery may be indicated
- Can be classified as either:
- Restrictive e.g. gastric banding, intra-gastric balloon
- Malabsorptive e.g. sleeve gastrectomy, Roux-en-Y bypass or biliopancreatic diversion with duodenal switch
Gastric banding
- Adjustable gastric band placed around proximal stomach via a laparoscopic approach
- A subcutaneous injection port is placed over the xiphisternum to allow alteration of the size of the restriction
- The aim is to induce early satiety by reducing gastric volume
- It is generally not a painful procedure, although the band can slip and cause pain
Intra-gastric balloon
- Endoscopically placed inflatable silicon balloon to reduce gastric volume and cause early satiety
Sleeve gastrectomy
- Laparoscopic, permanent reduction in stomach volume by approximately 80%
- A 34Fr bougie/OGT is placed per-orally and placed against the lesser curvature of the stomach
- It is used as a guide to staple the stomach into a banana shape
- It provides effective weight loss similar to Roux-en-Y bypass, but is simpler and with lower morbidity & mortality rates
- The most serious complication is a gastric leak, which typically occurs at the GOJ
Roux-en-Y gastric bypass
- Complex laparoscopic procedure involving:
- A 'Roux' loop of small bowel anastomosed to a small stomach pouch, which bypasses the distal stomach, duodenum and jejunum
- A bilio-pancreatic limb, end-to-side small bowel anastomosed to deliver digestive fluid to the bowel
- The most painful of the bariatric procedures
- Various post-operative risks including:
- Anastamotic leak
- Vitamin- and mineral-deficiencies
- Weight (re)gain
Biliopancreatic diversion with duodenal switch (BPD/DS)
- A small tubular stomach pouch with intact pylorus is created and plumbed into the ileum to create a 'digestive loop'
- A separate 'biliopancreatic loop' is created from the duodenum and jejunum and anastamosed to the digestive loop distally
- This rearranges the small intestine to separate the flow of food from the flow of bile and pancreatic juices, creating relative malabsortion and fewer calories absorbed
- Typically a two-stage procedure
- Associated with:
- Less risk of GI ulceration
- Less hunger
- More normal eating as the gastric pouch is bigger than in other malabsorptive procedures
- Lower risk of 'dumping syndrome'
- Rapid weight loss which may be better sustained than in other surgeries
Perioperative management of the patient undergoing bariatric surgery
- Patients should be managed by an MDT including bariatric-experienced staff, ideally in a bariatric centre
- Median age is 43yrs, with a median BMI of 44kg/m2 and an overall female preponderance of 77%
History and examination
- Pre-operative assessment should evaluate common coalescing diseases:
- T2DM (23%)
- Hypertension (41%)
- Ischaemic heart disease
- OSA (18%)
- GORD (25%) Depression (17%)
- Bariatric surgery is an elective procedure and these comorbidities should be optimised prior to surgery
- Thorough airway assessment as higher incidence of difficult intubation
Investigations
- Bloods inc. FBC, U&E, LFT, coagulation, group and save
- ECG
- Consider TTE if history indicative of cardiac dysfunction or prior ischaemic heart disease
- ± CPET
Risk assessment
- Risk prediction can be facilitated with the Obesity Surgery Mortality Risk Score (OS-MRS)
- It is only validated in bariatric surgery but may be used in non-bariatric surgery
- The score can be used to plan the need for postoperative care
- A score of 4-5 indicates a high-risk patient and should prompt consideration of post-operative admission to critical care
Risk Factor | Score |
BMI >50kg/m2 | 1 |
Male gender | 1 |
Hypertension | 1 |
Age >45yrs | 1 |
Any risk factor for PE: OSA/OHS Previous VTE Right heart failure Pulmonary hypertension IVC filter inserted per-operatively |
Max 1 |
Liver diet
- Patients undergo a pre-operative weight loss regimen for 2 - 4 weeks before surgery
- Regimen involves 800kcal/day
- Reduces liver volume by 16 - 20%, improving surgical access
- Reduces post-operative complications
General equipment
- Suitable gowns and theatre-wear of appropriate size
- Appropriate transfer equipment should be available:
- Patient should maintain their own mobility as much as possible
- Equipment such as chairs, trolleys and beds should be safe to use at patient’s weight
- May require use of hover mattresses or similar devices
- Adequate staff members present to facilitate safe transfer
- Oxford HELP pillow or other mode of ramping
- Large IPC's or TEDS (10x increased risk DVT)
- Sufficient staff to move the patient
- Once on the operating table require:
- Extra-wide extensions or arm gutters
- Gel pads to protect pressure points
Anaesthetic equipment
- Large NIBP cuff
- May need to use forearm for NIBP monitoring
- Do not routinely require intra-arterial BP monitoring
- Predict difficult intubation therefore VL and associated difficult airway kit
- Ultrasound machine in case of difficult vascular access
- Long spinal/epidural and regional needles
- Ventilator capable of delivering suitable driving pressure and PEEP
- Neuromuscular monitoring as higher potential for incomplete reversal of NMBA
Induction and airway
- Obesity is associated with a higher risk of developing airway problems under anaesthesia, with NAP4 revealing:
- 2x rate of adverse events (esp. with SAD)
- Higher failure of rescue techniques
- Routine airway assessment should be performed, with particular emphasis on identifying:
- Mallampati III (predicts difficult facemask ventilation and intubation)
- Neck circumference >42 cm (one of the best predictors of difficult intubation)
- BMI >50 kg/m2 (independent predictor of both difficult intubation and facemask ventilation)
- The presence of a beard
- Symptoms of gastro-oesophageal reflux disease
- Induction should take place in theatre to mitigate unnecessary transfer risk and allow greater space and access to assistance
- Should be ramped or sat upright; maintains FRC, reduces dyspnoea and facilitates BVM/laryngoscopy
- Need appropriate equipment to facilitate intubation, including video laryngoscopy and adjuncts
- Routine fibreoptic intubation is not recommended
- An airway plan should be vocalised and DAS guidelines followed
- FONA may be more difficult with a higher risk of complications
- May be appropriate in high risk cases to identify the depth of the cricothyroid membrane, vascular tissue, and mark relevant landmarks to improve the chance of success
- Obesity is associated with an increased incidence of known risk factors for aspiration
- However, obesity alone does not increase risk of reflux and pulmonary aspiration
- In the absence of other risk factors, routine performance of RSI is not required
- There is a higher risk of hypercapnoea and hypoxia, as increased body tissue mass and work of breathing leads to greater oxygen consumption and CO2 production
- FRC is reduced to closing capacity and causes atelectasis and hypoxia, due to:
- Excess adipose tissue reduces chest wall compliance
- Lying supine
- General anaesthesia
- Pneumoperitoneum
Maintenance
- NAP5 revealed an increased incidence of awareness in obese patients shortly after induction of anaesthesia, attributable to the rapid redistribution of IV agents
- In order to reduce occurrence, should ensure:
- Adequate dosing of IV agent
- Prompt delivery of maintenance anaesthetic agent
- Further bolus(es) of anaesthetic agent before airway manipulation or protracted airway manoeuvres
- Consider using processed EEG-based depth of anaesthesia monitoring to reduce risk of awareness
- TIVA with propofol offers a number of potential advantages over volatile anaesthesia for the obese patient:
- Rapid offset of action
- ‘Clear-headed’ emergence
- Reduced incidence of laryngospasm
- Reliable clearance of hypnotic agents
- Reduced PONV
- Maintained anaesthesia during protracted airway manipulation
- Need to be mindful of the idiosyncrasies of the chosen pharmacokinetic model as obese patients were often excluded from the initial development
- Using volatile agents with a rapid offset of action (low blood:gas partition coefficient) e.g. desflurane/sevoflurane should:
- Limit adipose absorption
- Reduce risk of re-sedation at emergence
Ventilation
- Obesity is an independent risk factor for developing postoperative pulmonary complications
- Current recommendations for ventilation include:
- Lung protective volumes (6 - 8ml/kg)
- Plateau pressure <30cmH2O
- PEEP titrated to respiratory and cardiovascular state, typically 8 - 10cmH2O
- Use of recruitment manoeuvres where there is suspicious of atelectasis/collapse
- Minimising the effect of positioning on ventilation is important although often supine or reverse Trendelenburg which is less of an issue
Reversal and emergence
- The hazards of airway/respiratory problems during emergency are greater in the obese population
- To mitigate this, ensure:
- Ventilate with 100% FiO2 until PEO2 >0.9
- Patient is sat upright
- Full reversal of NMBA with appropriate doses of sugammadex or neostigmine
- Only extubate once fully awake
Analgesia
- Multi-modal opioid-sparing analgesia is ideal to reduce risk of PONV and negative opioid-associated effects in this cohort
- This includes:
- Regular simple analgesia such as paracetamol ± NSAIDs if not contraindicted
- Local anaesthetic wound infiltration ± infusion catheters e.g. rectus sheath/li>
- Adjuncts such as magnesium, ketamine, clonidine
- Opioids e.g. morphine IV or as a PCA post-operatively
- IV lidocaine 1.5mkg/kg did not provide additional analgesic benefit over-and-above a morphine PCA (BJA, 2023)
Other elements of intra-operative care
- For malabsorptive procedures it is common to check the integrity of staple lines/anastamosis
- OG tube is advanced through the surgical anastomosis to prevent backwall suturing of anastomosis
- Surgical and anaesthetic communication & coordination is important to guide the OGT through the anastomosis
- Methylene blue 60mL is injected via the OGT at the end of the case to pressurize the proximal pouch and look for leaks
- Ensure meticulous pressure care; prolonged pressure can cause ischaemia and rhabdomyolysis (classically gluteal ischaemia)
- Appropriate intra-operative VTE prophylaxis e.g. intermittent pneumatic compression devices
- Temperature control
- Glucose management if patient is diabetic
PONV
- Patients are typically high risk of PONV, by virtue of being mostly female, <50yrs old, undergoing laparoscopic surgery and often needing opioids
- Multi-modal anti-emesis and reducing opioid use is effective e.g. two intra-operative agents with resuce medication in recovery
Anastomotic leaks
- A rare (0.8 - 1.5%) complication although serious, increasing both morbidity (to 61%) and mortality (to 15%)
- Higher risk in those:
- With a BMI >50kg/m2
- With metabolic syndrome
- Undergoing revision surgery
- Presents 24 - 72hrs post-operatively, typically with a persistent tachycardia ± abdominal pain, fever or outright sepsis
Venous thromboembolism
- High risk VTE so mechanical compression devices + actual BW dosing of LMWH is required
Bleeding
- Relatively common (up to 4%), causing melaena, haematemesis and reduced post-operative haemoglobin concentration
- Supportive management is usually all that's required, and hypovolaemia is rare
- Typical sites are either the staple line (sleeve gastrectomy) or anastomosis sites (gastric bypass)
Other risks
- Higher risk of pulmonary complications from being obese
- Nutritional deficiency is common, and dietetic-involved protocol-driven meal plans are recommended