- Evaluate circulation as in adults; HR, CRT, peripheral perfusion, blood pressure, mentation ± urine output
- Paediatric patients compensate well; hypotension is a late sign of decompensated shock and may be rapidly followed by bradycardia and arrest
- Obtain vascular access, with early IO access if IV access attempts have failed
- Send blood for VBG, Group and cross-match, FBC, U&E, clotting inc. fibrinogen
- Fluid resuscitation initially with 10ml/kg boluses of warmed crystalloid
- Consider permissive hypotension to a systolic BP of 80-90mmHg or a palpable radial pulse until haemorrhage is curtailed
- Give TXA 15mg/kg as a bolus as soon as possible, within 3hrs of injury
- Then infused 2mg/kg/hr for either 8hrs or until bleeding stops
Major haemorrhage and transfusion
- Activate paediatric major haemorrhage protocol
- Early use of warmed blood products instead of vasopressors
- 10ml/kg warmed O-negative or cross-matched pRBC
- Octaplas (FFP96) 5-10ml/kg boluses in a 1:1 ratio with pRBC
- Give platelets 10ml/kg (if under 15kg) or 1 adult pack (if >15kg) if either:
- 20ml/kg pRBCs have been transfused
- Platelet count <75 x x109/L
- Cryoprecipitate 10ml/kg if either:
- Fibrinogen <1g/L
- 40ml/kg of blood products have been administered
- Aim ionised calcium >1mmol/L
- Give 0.1ml/kg 10% calcium chloride after every 20ml/kg transfused products or if ionised calcium <1
- Alternatively use 0.5ml/kg 10% calcium gluconate
- Treat transfusion-associated hyperkalaemia, targetting a potassium <6mmol/L
- Give 0.1units/kg insulin actrapid in 10ml/kg 10% dextrose
- Monitor temperature and target 36'C
- High body surface area to mass ratio means hypothermia develops quickly; steps to prevent hypothermia should be undertaken
- Use oesophageal temperature probe in the unconscious child
- Warm fluids e.g. Ranger, Belmont
- Warm, humidified breathing circuits e.g. use HME
- Under-mattress or forced-air warmers
Factor |
Target |
Intervention |
Hb |
>80g/L |
RBC transfusion |
Platelets |
>75 x 109/L |
Platelet transfusion |
Fibrinogen |
>2g/L |
Cryoprecipitate | PCC | FFP |
Prothrombin time (INR) & APTTr |
<15s (<1.5) |
FFP |
Ionised calcium |
>1mmol/L |
IV calcium
|
Temperature |
>35°C |
Active warming |
pH |
>7.2 |
Resuscitation | I&V |
Lactate |
<4 |
Resuscitation |