- Overall incidence 0.74% (females) to 6.6% (males)
- Highest incidence in the first year of life
- Neonatal incidence 1-5%
- Premature infants have an increased risk of 11%
- Extremely low birth weight (<1kg) infants the rate is 40%
- 60% are right-sided, 30% left
- 10% are bilateral, and this is a more common occurrence in premature or low birth weight infants
- Rates of incarceration are higher in premature infants
Risk Factors
- Male
- Prematurity
- Low birth weight
- Associations
- Urological abnormalities: hypospadias, cryptorchidism, bladder extrophy
- Raised intra-abdominal pressure e.g. ascites, VP shunt, peritoneal dialysis
- Abdominal wall defects i.e. exomphalos, gastroschisis
- CF
- Mucopolysaccharidoses
- Connective tissue disorders: Ehlers-Danlos syndrome, Marfan syndrome
- Family history