FRCA Notes


Intra-Operative Cardiac Arrest

This page is dedicated to intra-operative cardiac arrest, rather than cardiac arrest occurring outside the theatre environment.

There's not yet been an SAQ/CRQ on intra-operative arrest, but SBA/MTF questions on the topic are fairly common.

Resources


  • Overall incidence 1 in 3,000
    • In elective surgery only: 1 in 6,500
    • For ASA 1 patients: 1 in 10,600
    • For ASA 1 or 2 patients: 1 in 8,500
  • 56% male
  • Median age 60.5yrs

Patient factors

  • Very young age
  • Frailty
  • Comorbid
  • Higher ASA grade:
    • ASA 1-2: 27%
    • ASA 3: 37%
    • ASA 4-5: 4-5: 37%

Surgical factors

  • Emergency surgery; 71% of arrests occurred during non-elective cases, despite these cases only representing 36% of all those included
  • Complex or major surgery; 60% of arrests occurred during complex/major surgical cases, despite these cases only representing 28% of all those included
  • Out of hours surgery
  • Specific surgical specialties:
    • Ortho-trauma (12%)
    • Lower GI (10%)
    • Cardiac surgery (9.4%)
    • Vascular surgery (8.1%)
    • Interventional cardiology (5.5%)

Location

    • Main theatre suite: 51%
    • Critical care: 12%
    • Anaesthetic room: 11%
    • Cardiac cath lab: 6.1%

Phase of surgery

  • Intra-operative under GA (34%)
  • Post-operative after recovery (17%)
  • Induction (13%)
  • Between induction and start of surgery (13%)

  • The AAGBI cover pretty much all bases by describing the cause of arrest as likely to be 'something related to surgery or anaesthesia; the patient’s underlying medical condition; the reason for surgery or equipment failure'

  • The standard reversible causes of cardiac arrest (4Hs and 4Ts) are still applicable, though the Resus Council say there should be a focus on identifying and correcting:
    • Hypovolaemia e.g. from anaphylaxis or bleeding
    • Hypoxia e.g. from airway issues
    • Tension pneumothorax
    • Thrombosis i.e. pulmonary embolism

Specific causes

  • 31% of death from cardiac arrest in NAP7 were deemed 'inexorable'; in 32% of cases there were elements of poor care before cardiac arrest occurred
Primary specific causes of intra-operative arrest as assigned by the NAP7 panel
Major haemorrhage (17%)
Bradyarrhythmia (9.4%)
Cardiac ischaemia (7.3%)
Septic shock (6.8%)
Isolated, severe hypotension (6.1%)
Severe hypoxaemia (6.1%)
Anaphylaxis (4%)
Vagal outflow (3.7%)
BCIS (2.3%)
High neuraxial block (0.7%)
Laryngospasm (0.6%)

Rhythms

  • Overall non-shockable rhythms (82%) were much more common
  • Breakdown by rhythm
    • 52% PEA
    • 15% asystole
    • 15% bradycardia
    • 6% VT
    • 6% VF

  • The management of intra-operative cardiac arrest mostly follows a standard ALS algorithm
  • Differences in considerations and management are described below

Initial management

  • The opening gambit should be familiar:
    • Declare cardiac arrest and (delegate someone to) start chest compressions
    • Turn off any maintenance anaesthetic
    • Call for help and the cardiac arrest trolley
  1. Check the position of the airway and ensure its patency; NB if EtCO2 is absent then presume oesophageal intubation until absolutely excluded

  2. Increase the FiO2 to 1.0
    • Ensure the breathing system is working adequately
    • Can manually ventilate the patient or use the ventilator; if using the ventilator use a volume control mode

  3. Ensure adequate chest compressions
    • Ensure adequate access (IV or IO)
    • Drugs are the same, although give adrenaline incrementally rather than as a 1mg bolus
  • Management otherwise follows the standard ALS algorithm

Differences in management

  • The Resus Council say we should 'use ultrasound to guide resuscitation' but offer no further information on what that means
  • With reference to the relevant reversible courses of cardiac arrest, it is presumably intended to be useful in:
    • Checking for oesophageal intubation causing hypoxia, as per the AAGBI guidelines (2022)
    • Looking for evidence of pneumothorax
    • Point of care echocardiography, looking at the right heart to support a suspected diagnosis of PE (as well as general assessment of cardiac function)
    • Aiding assessment of volume status

  • The other tidbits from the Resus Council relate to alternative methods of CPR, namely:
    • Consider open cardiac compression in place of standard close cardiac compression
    • Consider extra-corporeal CPR if conventional CPR is failing e.g. ECMO, CPB

  • In NAP7, 75% achieved ROSC, which is higher than for other in-hospital cardiac arrests
  • Of those who achieved ROSC, 44% survived to discharge
  • Of those discharged from hospital, 88% had a good functional outcome (mRS 0-3)

  • Of the anaesthetists who experienced a perioperative cardiac arrest, 4.5% reported an impact on their subsequent ability to deliver patient care

Organisation of services

  • Standardised, age-appropriate resuscitation equipment available in every site where anaesthesia takes place

  • Recognise, and modify techniques for, high-risk cardiovascular settings, e.g.:
    • Hypovolaemia with cardiovascular instability
    • Those with frailty or elderly patients
    • Vascular surgery
    • Those with pre-existing bradycardia ± expected vagal stimulus during surgery

  • Training, practice and institutional protocols for managing predictable perioperative complications e.g. cardiac arrest, haemorrhage, anaphylaxis and airway difficulty

  • Trust policy for the management of an unexpected death associated with anaesthesia and surgery

  • The Independent Healthcare Provider Network (IHPN) and Private Healthcare Information Network (PHIN) should work with commissioners of care, regulators and inspectors to improve engagement with safety-related national audit projects in the independent hospital sector to assess the quality and safety of care delivered

  • Greater clarity in adult and paediatric cardiac arrest guidelines pertaining to:
    • When to start chest compressions
    • Dosing of adrenaline
    • Indications for use of calcium and bicarbonate
    • Indications for eCPR (e.g. CPB or ECMO)

Before

  • Use validated risk-scoring tools routinely as part of pre-operative assessment and shared decision making

  • Patients should be provided with a realistic assessment of likely outcomes of their treatment, routinely including important risks such as risk of death

  • Treatment escalation inc. DNACPR recommendations should be discussed and documented as early as possible preoperatively, if:
    • Clinical frailty score ≥5
    • ASA 5
    • Objective risk scoring of mortality >5%

  • Infants and neonates should be recognised as high risk of airway difficulty and, when critically ill, of cardiovascular collapse soon after induction; senior and expert care at all times should be available

During

  • Regardless of location, anaesthesia should not be performed unless appropriate preoperative observations, investigations, risk assessment and team brief have been performed

  • Robust supervision, including clear processes for contacting assistance during emergency, should be in process, especially for paediatric or remote cases

  • A standard procedure to effectively call for help, which includes an audible alarm, should be provided across all locations where anaesthesia takes place

  • Consistent monitoring as per AAGBI guidelines

  • Level of monitoring should match patient risk, with a lower threshold for continuous invasive arterial blood pressure monitoring in theatre/recovery

  • High-risk or deteriorating patients should be anaesthetised in theatre on the operating table

  • Training and competency in administering IV adrenaline (bolus and infusion)

  • In monitored patients in early cardiac arrest or a severe low flow state, initially give small doses of intravenous adrenaline (eg 50 µg in adults or 1 µg/kg in children) or an infusion of adrenaline, and if return of spontaneous circulation (ROSC) is not achieved within the first 4 minutes (about two 2-minute cycles of CPR) of cardiac arrest, give further adrenaline boluses using the standard cardiac arrest dose (1 mg in adults or 10 µg/kg in children)

After

  • All cardiac arrests should be reviewed to understand the cause, discover potential learning and support staff; learning should be shared across the whole perioperative team

  • All cases of cardiac arrest should be communicated to the patient, next of kin, or parents if the patient is a child, as part of the duty of candour